The Diagnostic Approach to Central Adrenocortical Insufficiency (CAI) in Thalassemia
نویسندگان
چکیده
In thalassemia major (TM) patients, impairment of the hypothalamic-pituitary-adrenal (HPA) axis secondary to hemosiderosis of the pituitary gland and/or adrenal glands is well established. In TM, hypocortisolism is paucisymptomatic or causes nonspecific symptoms. Although adrenal insufficiency (AI) is rare; an acute crisis may occur in the event of acute cardiac decompensation, stress, or sepsis. 1-3
منابع مشابه
The ICET-A Survey on Current Criteria Used by Clinicians for the Assessment of Central Adrenal Insufficiency in Thalassemia: Analysis of Results and Recommendations
BACKGROUND In March 2015, the International Network of Clinicians for Endocrinopathies in Thalassemia and Adolescent Medicine (ICET-A) implemented a two-step survey on central adrenal insufficiency (CAI) assessment in TM patients and after analysis of the collected data, recommendations for the assessment of hypothalamic-pituitary- adrenal (HPA) axis in clinical practice were defined. METHODS...
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